Citicoline Supplement 250mg – 90 Capsules | >98% Ultra Pure CDP Choline | Made in Canada

Understanding Citicoline: The Premium Brain Nutrient

Citicoline, scientifically known as cytidine 5'-diphosphocholine or CDP-choline, represents one of the most researched and respected nootropic compounds in nutritional science. This naturally occurring molecule has been studied extensively since its discovery in the 1950s, when researchers first identified its unique role in cellular membrane synthesis and neurotransmitter production. Unlike basic choline sources, citicoline exists as an intermediate compound in the biosynthesis of phosphatidylcholine, a critical component of brain cell membranes.

The history of citicoline supplementation began in Japan and Europe, where it gained recognition for its superior bioavailability compared to conventional choline supplements. What sets CDP choline apart from other forms like choline bitartrate or choline chloride is its molecular structure—it combines choline with cytidine, allowing it to cross the blood-brain barrier with remarkable efficiency. This pharmaceutical-grade compound delivers choline directly to neural tissues, where it's most needed for optimal brain function.

What Makes Our Citicoline Supplement Different

At Herba, we've formulated our citicoline supplement with a commitment to purity and potency that sets us apart in the Canadian supplement market. Each capsule contains 250mg of citicoline sodium, independently verified at greater than 98% purity—with our most recent third-party testing showing 100% purity. This exceptional quality ensures you're receiving authentic CDP choline, not diluted with inferior choline sources that some manufacturers use to reduce costs.

We manufacture our citicoline supplement in Canada, adhering to cGMP manufacturing standards that represent the gold standard in pharmaceutical production. Every batch undergoes rigorous third-party testing to verify purity, potency, and safety. Our product has received a Natural Product Number (NPN) from Health Canada, demonstrating compliance with Canadian regulatory standards for natural health products.

Clean Formula, Maximum Effectiveness

Our citicoline formula reflects our philosophy that premium supplements require premium ingredients throughout—not just in the active compound. The formula contains no gluten, dairy, sugar, soy, or egg, making it accessible to individuals with various dietary restrictions and preferences.

The 250mg dosage per capsule allows for flexible use, with our recommended serving of two capsules daily providing 500mg of pure CDP choline. This concentration represents a sweet spot identified in scientific research, offering meaningful support without unnecessary excess. Each bottle contains 90 vegetable capsules, providing a full 45-day supply when taken as directed—a three-month supply offers exceptional value for those committed to consistent supplementation.

The Science of Bioavailability

What distinguishes citicoline from other choline supplements is its superior bioavailability profile. When you consume our CDP choline capsules, the compound is readily absorbed in the intestinal tract. Once in the bloodstream, citicoline's unique molecular structure enables it to efficiently penetrate the blood-brain barrier—a selective barrier that protects the brain from potentially harmful substances while allowing essential nutrients through.

After crossing into brain tissue, citicoline undergoes enzymatic conversion, yielding both choline and cytidine. The choline component serves as a precursor for acetylcholine synthesis and contributes to phosphatidylcholine production in cell membranes. The cytidine component supports various cellular processes, including RNA and phospholipid synthesis. This dual-action mechanism explains why citicoline demonstrates higher bioavailability compared to basic choline supplements that only provide the choline molecule.

Quality Manufacturing in Canada

We manufacture our citicoline supplement in Canada, taking advantage of the country's rigorous regulatory framework for natural health products. Canadian manufacturing standards are among the most stringent globally, requiring detailed documentation, quality control procedures, and regular facility inspections. Our manufacturing partnership follows cGMP protocols, which encompass everything from raw material verification to final product testing.

Third-party testing represents a cornerstone of our quality assurance program. Independent laboratories analyze each batch for purity, verifying that our citicoline meets or exceeds the stated 98% minimum purity. These same tests screen for potential contaminants, heavy metals, and microbial contamination, ensuring every capsule meets the highest safety standards. This transparency and commitment to testing distinguish premium supplements from those manufactured with less oversight.

Recommended Uses

Our Herba Citicoline supplement is formulated to help support your cognitive wellness with two specific, recognized uses: Helps to improve sustained attention. Helps to support cognitive health and brain function in older adults. These recommended uses reflect the recognized applications of citicoline supplementation based on scientific understanding and regulatory approval.

Medicinal ingredient (per capsule):

• Citicoline (Citicoline sodium) - 250 mg

Non-medicinal ingredients

• Brown rice flour, hypromellose, l-leucine

Directions
Adults (18 years and older): Take 1 capsule, 2 times per day.

Warnings: Ask a health care practitioner before use if • you are taking dopaminergic or cholinergic drugs • you are pregnant or breastfeeding • you have an attention deficit disorder with or without hyperactivity (ADD or ADHD). When using this product you may experience headaches or gastrointestinal disturbances.

Q. What is the difference between citicoline and regular choline supplements?

A. Citicoline (CDP-choline) is a more advanced form of choline supplementation compared to basic choline sources like choline bitartrate or choline chloride. The key difference lies in bioavailability—citicoline combines choline with cytidine in a molecular complex that efficiently crosses the blood-brain barrier. Regular choline supplements provide only the choline molecule, which has limited ability to reach brain tissue. Our ultra-pure citicoline delivers both choline and cytidine components directly to neural tissues, making it the most bioavailable choline supplement available.

Q. How should I take this citicoline supplement?

A. Adults 18 years and older should take 1 capsule, 2 times per day. We recommend taking the capsules with meals to optimize absorption, though they can be taken with or without food. Each bottle contains 90 capsules, providing a 45-day supply at the recommended dosage of 2 capsules daily. For best results, maintain consistent daily use as part of your wellness routine.

Q. Is your citicoline supplement suitable for vegans and people with dietary restrictions?

A. Yes, our citicoline formula is completely vegan-friendly and accommodates most dietary restrictions. We use vegetable capsules made from hypromellose (plant-derived cellulose) rather than gelatin. The formula is free from gluten, dairy, sugar, soy, and egg. It's also non-GMO, ensuring compatibility with clean eating and plant-based lifestyles.

Q. What does ">98% purity" mean and why does it matter?

A. The >98% purity specification means that more than 98% of the citicoline in each capsule is authentic CDP-choline, with minimal fillers or impurities. This exceptional purity level is verified through third-party laboratory testing, with our most recent batch testing at 100% purity. Purity matters because some manufacturers blend small amounts of actual citicoline with cheaper choline sources, diluting the effectiveness. Our ultra-pure formula contains only genuine citicoline sodium, ensuring you receive the full benefits of this premium nootropic compound.

Q. How is your product tested for quality and safety?

A. We implement a comprehensive testing protocol that includes third-party laboratory analysis of every batch. Independent labs verify the purity and potency of our citicoline, confirming it meets or exceeds 98% purity standards. Testing also screens for heavy metals, microbial contamination, and other potential impurities. Our manufacturing follows cGMP standards, which require documented quality control procedures throughout production. Additionally, our product holds a Natural Product Number (NPN) from Health Canada, indicating it meets Canadian regulatory requirements for natural health products.

Q. Why is this product manufactured in Canada?

A. We manufacture in Canada because Canadian regulatory standards for natural health products are among the world's most rigorous. Health Canada requires detailed quality control documentation, regular facility inspections, and specific manufacturing protocols that ensure product safety and efficacy. Canadian cGMP standards mandate strict raw material verification, environmental controls, and final product testing. Manufacturing domestically also allows us to maintain closer oversight of production and respond quickly to any quality concerns.

Q. Can I open the capsules if I have difficulty swallowing them?

A. Yes, the capsules can be opened and the contents mixed with water, juice, or food if you prefer not to swallow capsules. However, we recommend swallowing the intact capsules when possible, as the vegetable capsule helps protect the citicoline during digestion and ensures optimal release in the intestinal tract. If you do open the capsules, consume the entire contents immediately and take with food or liquid.