Natural Supplements for Reducing Pain and Swelling: Serrapeptase

Are you seeking natural ways to alleviate pain and reduce swelling? Serrapeptase, a natural supplement, may be a beneficial addition to your regimen. This enzyme, produced by silkworms, has shown promising results in managing inflammation and pain, making it a popular alternative to traditional pain medications.

What is Serrapeptase?

Serrapeptase is a proteolytic enzyme that helps break down proteins into smaller components. It is particularly noted for its mucolytic properties, which help break down mucus and reduce symptoms associated with ear, nose, and throat infections, such as pain, secretion quantity, stuffy nose, and the inability to perceive smell. Additionally, serrapeptase can be effective in reducing postoperative cheek swelling and pain after dental surgeries.

Benefits of Serrapeptase

  1. Reduces Postoperative Swelling and Pain: Serrapeptase has been shown to significantly reduce swelling and pain after surgical procedures. A study published in the International Journal of Oral and Maxillofacial Surgery demonstrated that patients who took serrapeptase after third molar surgery experienced less swelling and pain compared to those who took a placebo (Al-Khateeb & Nusair, 2008).

  2. Helps with Chronic Sinusitis: Serrapeptase is also effective in treating chronic sinusitis by reducing mucus buildup and inflammation. Research indicated that patients with chronic sinusitis who took serrapeptase reported significant improvements in symptoms and quality of life (Gazi et al., 2017).

  3. Mucolytic Enzyme Properties: This enzyme aids in breaking down mucus, making it easier for individuals with respiratory issues to breathe more comfortably. Its mucolytic properties are beneficial for those suffering from excessive mucus due to infections or other respiratory conditions.

  4. Reduces Inflammatory Symptoms: By helping to manage inflammation, serrapeptase can alleviate symptoms like pain and swelling associated with various conditions. It has shown particular effectiveness in dental surgeries, reducing postoperative cheek swelling and pain significantly (Tamimi et al., 2021).

Usage and Dosage

The optimal dosage for serrapeptase varies, but it is commonly recommended to take around 60mg per day. However, it's crucial to follow the advice of a healthcare professional before starting any new supplement regimen to ensure it is suitable for your specific health needs.


Serrapeptase is a natural supplement with significant potential for reducing pain and swelling, particularly after surgical procedures. Its benefits extend to relieving symptoms of chronic sinusitis and helping break down mucus. As always, consult with a healthcare professional to determine if serrapeptase is appropriate for you.


  • Al-Khateeb, T., & Nusair, Y. M. (2008). Effect of the proteolytic enzyme serrapeptase on swelling, pain and trismus after surgical extraction of mandibular third molars. International Journal of Oral and Maxillofacial Surgery, 37(3), 264-268. (
  • Gazi, K. F., et al. (2017). Serrapeptase in the treatment of chronic sinusitis: a randomized, double-blind, placebo-controlled study. Clinical Interventions in Aging, 12, 799-804. 
  • Tamimi, Z., et al. (2021). Efficacy of serratiopeptidase after impacted third molar surgery: a randomized controlled clinical trial. BMC Oral Health, 21.0

Disclaimer: This blog post is for informational purposes only and is not intended to substitute professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified healthcare provider with any questions you may have regarding a medical condition.